This theme comes with a lot of module positions. The blue module positions allow to choose a module layout which defines the module alignment and proportions:
parallel, first doubled, last doubled, stacked
The two available sidebars, highlighted in red, can be switched to the left or right side and their widths can easily be set in the theme administration.
For modules in the blue and red positions you can choose different module styles. Take a look at the module variations page to get an overview.